{"id":413,"date":"2025-09-22T14:38:04","date_gmt":"2025-09-22T14:38:04","guid":{"rendered":"https:\/\/imardgroup.com\/web\/?page_id=413"},"modified":"2025-10-01T13:31:35","modified_gmt":"2025-10-01T13:31:35","slug":"research-evidence","status":"publish","type":"page","link":"https:\/\/imardgroup.com\/web\/research-evidence\/","title":{"rendered":"Evidence-based syntheses in mental health"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Evidence-based syntheses in mental health<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/ChatGPT-Image-Sep-22-2025-04_57_57-PM-e1758616094564.png\" alt=\"\" class=\"wp-image-447\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p>We carry out large-scale evidence syntheses\u2014including meta-analyses, mega-analyses, and umbrella reviews\u2014on the variables and processes involved in mental disorders. These methods allow us to combine results from many independent studies, increasing statistical power and providing a clearer picture of consistent findings across the field. While much of our work centers on neuroimaging results, we also investigate clinical risk factors and prognostic markers that help explain why some individuals experience worse outcomes than others.<\/p>\n\n\n\n<p>To advance this line of research, we have developed and validated widely used methodological tools such as Seed-based d Mapping, which has become a standard in neuroimaging meta-analysis. We also play an active role in international initiatives like the ENIGMA consortium, where large-scale collaborations and data sharing make it possible to address questions that no single group could tackle alone. Through these efforts, we aim to generate reliable, reproducible knowledge that informs both neuroscience and clinical practice.<\/p>\n<\/div>\n<\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"110\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/4925274-e1759143848375-1024x110.png\" alt=\"\" class=\"wp-image-565\" style=\"width:633px;height:auto\"\/><\/figure>\n<\/div>\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Last news:<\/em><\/h3>\n\n\n\n<p><\/p>\n\n\n      <div id=\"post-grid-lazy-478\" class=\"post-grid-lazy\"><img decoding=\"async\" alt=\"\" src=\"\" \/><\/div>\n    <script>\n      jQuery('#post-grid-lazy-478').ready(function($) {\n        $('#post-grid-lazy-478').fadeOut();\n        $('#post-grid-478   ').fadeIn();\n      })\n    <\/script>\n    <style type=\"text\/css\">\n      #post-grid-478 {\n        display: none;\n      }\n\n      .post-grid-lazy {\n        text-align: center;\n      }\n    <\/style>\n    <div data-options='{&quot;id&quot;:&quot;478&quot;,&quot;lazy_load&quot;:&quot;yes&quot;,&quot;masonry_enable&quot;:&quot;no&quot;,&quot;view_type&quot;:&quot;grid&quot;}' id=\"post-grid-478\" class=\"post-grid grid\">\n    \n\n\n    <div class=\"grid-items\">\n      <div class=\"item item-847 skin flat even 0 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/cosmocaixa.org\/es\/p\/bcnspiracy-2025\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/12\/deprisco_imard_bcnspiracy.pptx-1024x576.png\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/cosmocaixa.org\/es\/p\/bcnspiracy-2025\">Climate change and mental health at BCNspiracy 2025<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        Michele De Prisco discussed the impact of climate change on mental health at the 2025 edition of BCNspiracy, held at            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/cosmocaixa.org\/es\/p\/bcnspiracy-2025\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-796 skin flat odd 1 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/sepsm.org\/premios-sepsm-2025\/\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/11\/2025_-Joaquim-Radua-Castano-1024x643_cp2.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/sepsm.org\/premios-sepsm-2025\/\">Joaquim Radua receives the SEPSM Research Excellence Award 2025<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        Prof. Joaquim Radua, leader of the IMARD group, has received the Research Excellence Award from the Sociedad Espa\u00f1ola de Psiquiatr\u00eda            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/sepsm.org\/premios-sepsm-2025\/\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-640 skin flat even 2 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/www.thelancet.com\/journals\/lanpsy\/article\/PIIS2215-0366(25)00274-3\/abstract\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/1758632528726.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/www.thelancet.com\/journals\/lanpsy\/article\/PIIS2215-0366(25)00274-3\/abstract\">Lancet Psychiatry Commission on Climate Change and Mental Health<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        Joaquim Radua, Eduard Vieta, and Michele De Prisco have been appointed members of the commission led by Jurjen Luykx.            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/www.thelancet.com\/journals\/lanpsy\/article\/PIIS2215-0366(25)00274-3\/abstract\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-502 skin flat odd 3 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/article\/PIIS2589-5370(25)00345-1\/fulltext\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/gr3-e1759216781566.png?ver=1759217136\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/article\/PIIS2589-5370(25)00345-1\/fulltext\">Switch to Mania After Acute Antidepressant Treatment<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        Our new systematic review &amp; network meta-analysis (13 RCTs, &gt;1,300 participants) in eClinicalMedicine (part of The Lancet Discovery Science)...            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/article\/PIIS2589-5370(25)00345-1\/fulltext\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-669 skin flat even 4 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S016503272500744X\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/1-s2.0-S016503272500744X-gr2.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S016503272500744X\">Could eye-tracking serve as a future biomarker for bipolar disorder?<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        This meta-analysis revealed that individuals with BD tend to exhibit longer latency to first fixation, fewer fixations, shorter gaze duration...            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S016503272500744X\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-665 skin flat odd 5 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2833241\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/m_yoi250017f2_1751056133.31524.png\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2833241\">How are race and ethnicity reported and represented across RCTs of pharmacotherapies for mental disorders?<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        Our meta-analysis of 1683 RCTs (375,120 participants) in JAMA Psychiatry found significant underreporting of race and ethnicity and underrepresentation...            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2833241\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div><div class=\"item item-677 skin flat even 6 \">\n        <div class=\"layer-wrapper layout-\">\n        <div class=\"layer-media\"><\/div>\n  <div class=\"layer-content\">\n        <div\r\n        class=\"element element_0  element-media \">\r\n        <a target=\"_self\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0149763424004366\"><img loading=\"lazy\" decoding=\"async\" width=\"375\" height=\"225\" src=\"https:\/\/imardgroup.com\/web\/wp-content\/uploads\/2025\/09\/1-s2.0-S0149763424004366-gr2-e1759329402362.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" \/><\/a>    <\/div>\r\n    <div class=\"element element_1  title_link \">\r\n                    <a target=\"\"\r\n                href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0149763424004366\">Are emotion regulation strategies and mood symptoms correlated in bipolar disorder?<\/a>\r\n            <\/div>\r\n    <div class=\"element element_2  excerpt \">\r\n        In this meta-analysis of 15 studies, rumination emerged as the ER strategy most strongly associated with both depressive and (hypo)manic            <\/div>\r\n            <a class=\"element element_3  read_more \"\r\n            target=\"\"\r\n            href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0149763424004366\"><\/a>\r\n      <\/div>\n    <\/div>\n  <\/div>    <\/div>\n    <div class=\"pagination\">\n      <div class=\"paginate\">\n      <\/div>\n  <style type=\"text\/css\">\n    #post-grid-478 .pagination .page-numbers {\n      font-size: 16px;\n      color: #fff;\n      background: #646464;\n    }\n\n    #post-grid-478 .pagination .page-numbers:hover,\n    #post-grid-478 .pagination .page-numbers.current {\n      background: #4b4b4b;\n    }\n  <\/style>\n  <\/div>\n      <script>\n          <\/script>\n    <style type=\"text\/css\">\n    #post-grid-478 .element_0 {\n      display: block;font-size: 21px;line-height: normal;padding: 5px 10px;text-align: left; text-decoration: none;    }\n\n    #post-grid-478 .element_1 {\n      display: block;font-size: 21px;line-height: normal;padding: 5px 10px;text-align: left; text-decoration: none;    }\n\n    #post-grid-478 .element_2 {\n      display: block;font-size: 14px;padding: 5px 10px;text-align: left;    }\n\n    #post-grid-478 .element_3 {\n      display: block;font-size: 12px;font-weight: bold;padding: 0 10px;text-align: left;text-decoration: none;    }\n\n    #post-grid-478 .element_0:hover{}#post-grid-478 .element_1:hover{}#post-grid-478 .element_2:hover{}#post-grid-478 .element_3:hover{}  <\/style>\n  <style type=\"text\/css\">\n    #post-grid-478 {\n          }\n\n    #post-grid-478 .item {\n      padding: 0px;\n      background: #fff;\n          }\n\n    #post-grid-478 .item .layer-media {\n      height:auto;    }\n\n    @media only screen and (min-width: 0px) and (max-width: 767px) {\n      #post-grid-478 .grid-items {\n        display: grid;\n        grid-template-columns: 1fr ;\n        column-gap: 10px;\n        row-gap: 10px;\n              }\n\n      #post-grid-478 .item {\n        height:auto;      }\n    }\n\n    @media only screen and (min-width: 768px) and (max-width: 1023px) {\n      #post-grid-478 .grid-items {\n        display: grid;\n        grid-template-columns: 1fr 1fr ;\n        column-gap: 10px;\n        row-gap: 10px;\n              }\n\n      #post-grid-478 .item {\n        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These methods allow us to combine results from many independent studies, increasing statistical power and providing a clearer picture of consistent findings across the field. While much of our work centers&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_kad_post_transparent":"","_kad_post_title":"hide","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":"","_links_to":"","_links_to_target":""},"folder":[38],"class_list":["post-413","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/pages\/413","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/comments?post=413"}],"version-history":[{"count":0,"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/pages\/413\/revisions"}],"wp:attachment":[{"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/media?parent=413"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/imardgroup.com\/web\/wp-json\/wp\/v2\/folder?post=413"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}